Vitaminas y Minerales

Influence of Gene Variants in the Vitamin D Pathway

Abstract

Swapna Negi

The role of genetic variations in the vitamin D pathway in influencing individual vitamin D levels has been extensively studied. One particular gene variant, rs4588, has garnered attention due to its association with variations in vitamin D levels. Notably, the AA genotype of rs4588 has been linked to lower vitamin D levels, while the CC genotype is associated with higher levels. In this article, we delve into the intricate relationship between gene variants in the vitamin D pathway and their profound impact on vitamin D levels, shedding light on the broader implications for human health. The vitamin D pathway encompasses a series of biochemical processes responsible for the synthesis, transport and metabolism of vitamin D within the body.