Vitaminas y Minerales

Effect of Vitamin D Status on Clinical Pregnancy Rate in Case of Intracytoplasmic Sperm Injection (ICSI)

Abstract

Gebriel AEMA, Hassan FI, Abdel Latif EM, Hassan EA and Aref MI

Background: Vitamin D had been suggested to have a role in human reproduction. We aimed to investigate if vitamin D levels can predict implantation and clinical pregnancy rates in infertile females after Intra-cytoplasmic sperm injection (ICSI). Methods: Vitamin D levels had been evaluated prospectively by levels of serum 25-hydroxy-vitamin D (25[OH] D) levels, in a cohort of one hundred and fifty couples undergoing ICSI. Serum samples had been collected one week prior to oocyte retrieval. Patients had been classified according to vitamin D serum level into sufficient (≥ 75 nmol/L) or insufficient (<75 nmol/L). Results: 38.97% of included females had sufficient vitamin D levels mean while 61.03% had insufficient vitamin D levels. Females with sufficient levels of vitamin D had a higher clinical pregnancy rates per ICSI cycle (58.49%) in comparison to those with insufficient levels (36.14%; p 0.011)