Revista de diagnóstico y biomarcadores moleculares

Towards the Dreamed Biomarkers?

Abstract

Ranuncolo SM

Detection and determination of tumor biomarkers are made from tissue and blood collection. During the last decade new biological sources are feasible: circulating tumor cells and circulating nucleic acids. They are composing a new field named as liquid biopsy. The availability of next-generation sequencing and Digital-PCR among other techniques, led to the possibility of getting the most out of this “circulating material” that would mirror the genetic and epigenetic features of the tumor.