Revista de diagnóstico y biomarcadores moleculares

Biomarker Toxicology Effects

Abstract

Priyanka Dubey

Biomarkers are biochemical indicators that can be used to monitor biological changes in response to toxins or other stimuli. Researchers can measure and predict toxicological effects with the understand-ing that biomarkers within a biological system will fluctuate accord-ing to changes in that system. Modern gene therapy is often defined as a way that replaces one gene with another normal or therapeutic one. Although gene therapy has been used for several decades, but thus far it's not produced any clear-cut therapeutic results. Each year, an estimated 3 million babies worldwide, have birth defects. Quite 6 thousands single-gene disorders are currently known. Gene therapy is that the therapeutic delivery of virus gene into a patient’s cells to treat and cure diseases. The toxicological effects, which are actually the pharmacological effects of RCAs, but are perceived as adverse or toxicological effects, can be local or topical as well as systemic following absorption. In addition, the effects can be acute or long term. Also, the exposure can be acute, long, or repeated. Biomarkers can help doctors and scientists diagnose diseases and health conditions, find health risks in a person, monitor responses to treatment, and see how a person's disease or health condition changes over time. For example, an increased level of cholesterol in the blood is a biomarker for heart-attack risk.