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Antibiotics Susceptibility Profile of Wounds Isolates

Abstract

Abdulbagi Saeed Elbala, Abobaker Safe ELdeen Elkheir, Elnaim Bushra Ahmed and Babiker Saad Almugadam

Background: Wounds infection occurs due to contamination of wounds with microbes. Wounds infection can lead to serious complications as a result of localize or hematogenous spread of their causative pathogens.
Objective: This study aimed to evaluate the susceptibility of Enterobacteriaceae isolates to commonly use antibiotics for wounds infections.
Materials and Methods: This is a cross sectional, hospital and laboratory based study, carried out during period from October 2016 to August 2017. Wound swab was collected from each participant and cultured directly on blood and MacConkey agar; then incubated at 37°C aerobically for 24 hours. Each isolate was identified base on culture characters, Gram stain and manual biochemical tests. All isolates (hindered) which presumptively identified as a member of Enterobacteriaceae were further subjected to antimicrobial susceptibility testing (AST). Statistical analysis was performed using statistical package for social sciences (SPSS) software version 16.
Results: Antimicrobial susceptibility testing showed an emerge in antimicrobial resistant, among wounds isolates and there is significant difference in the susceptibility of this isolates to antibiotics. Most isolates were sensitive to IPM, and all were resistant to CTR 100%.
Conclusions: Antimicrobial susceptibility testing will be performed as a routine test for patients with wounds infections. Further studies must focus on other highly active and cheaper alternative therapies.

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