Biosensores y bioelectrónica

Electrochemical Sensor for the Determination of Adrenaline in Presence of Acetaminophen at Poly (Alanine) Modified Carbon Paste Electrode: A Cyclic Voltammetric Study

Abstract

Harisha KV, Swamy BEK*, Jayadevappa H and Ganesh PS

The electropolymerisation of DL-alanine was carried out at the surface of carbon paste electrode by cyclic voltammetric (CV) technique. The fabricated electrode was used for the electrocatalysis of adrenaline at neutral pH. The key parameters like influence of scan rate and concentration reveals the adsorption controlled process. The lower limit of detection was calculated to be 28.0 nM in the linear range of 10 to 60 μM by CV technique. Further, the poly (alanine) modified carbon paste electrode can be used for the selective determination of adrenaline in presence of acetaminophen. Overall, the fabricated electrode can be used as a promising analytical sensor in the determination of adrenaline in pharmaceutical and biological samples.