Revista de patología y diagnóstico quirúrgico

Bechet’s Disease (BD) is a rare entity. It’s a multi-systemic inflammatory disease of unknown etiology characterized by recurrent ulcers and vasculitis, mainly including oral cavity, eyes, gastrointestinal tract and joints. Crohn’s Disease (CD) is a chronic inflammatory disorder that may affect the same organs as BD, however more frequently the GI tract. Distinguish BD from CD can be very challenge due to the overlapping clinical presentation and similar morphology features on pathology biopsy specimens. Herein, we present a rare and interesting case which BD mimics IBD on the GI biopsies but with some unique findings. This is a case report of a 32-year-old, female, who first presented at ED with fatigue, weight loss, arthralgia, and erythema nodosum. One month later, patient was admitted for oral ulcers, skin rash, genital ulcers and melena. Treatment with prednisone was started at the time and further workup for BD versus IBD was initiated. Her GI biopsies show granulomatous vasculitis of esophagus and colon biopsies demonstrate overlapping features with CD.