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Unusual MRI Findings for a Drug Resistant Depression

Abstract

Halim Abboud and Georges L Nawfal

Background: The association between intracranial Dural Arteriovenous Fistulas (dAVF) and psychiatric disorders has been reported in a few anecdoctal reports Case presentation: A case of severe depression with dAVF is presented. The patient with depression showed poor response to antidepressants, and after a severe headache she was investigated and was found to have a dAVF. The DAVF was successfully treated withmcoil embolization. After this treatment, his depression was improved and the quantity of the antidepressants decreased. Conclusions: The findings in our case suggest a probable association between dAVF and treatment resistant depression caused by cerebral hypoperfusion especially of the left cerebral hemisphere. It may be necessary to evaluate cerebral vessels in patients suffering from depression by using MRA.

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