Medicina pulmonar y respiratoria

The Transpulmonary Passage of Cancer Cells: Historical Review

Abstract

Wilson IB Onuigbo

Macfarlane Burnet, who is far famed in oncology, recommended during his address on the morphogenesis of cancer that researchers ought to know the historical aspects of their field. In this context, in 1952, Zeidman and Buss used experimental animals to document the transpulmonary passage of cancer cells. However, they did not supply the historical background. Therefore, this paper collates the observations of the old masters in this field from 1845 to 1899.