Revista de inmunobiología

Mechanisms of Inflammation-Related Innate Immune Response Activation

Abstract

Alexander Blalock

Inflammatory diseases arise from dysregulated immune responses, and recent research has focused on the role of innate immunity in their pathogenesis. The innate immune system, comprising physical barriers, Pattern Recognition Receptors (PRRs) and immune cells, plays a crucial role in initiating and regulating inflammation. However, aberrant innate immune activation can lead to chronic inflammation and tissue damage. This article explores the significance of innate immunity in driving inflammation and highlights the emergence of targeted therapies aimed at modulating innate immune responses. By understanding the intricate mechanisms underlying innate immune dysregulation, researchers are developing novel therapies to treat a range of inflammatory diseases.