Revista de Oncología Integrativa

Inhibitory Influence of the Tumor Microenvironment on the Immune System's Efficacy: Implications for Cancer Therapeutics

Abstract

Labard Baras*

Drug resistance is a major challenge in the treatment of cancer. It refers to the ability of cancer cells to survive and continue growing despite exposure to anti-cancer drugs. This uncontrolled growth can result in the formation of a lump or mass called a tumor. These are non-cancerous growths that do not invade nearby tissues or spread to other parts of the body. They tend to grow slowly and are usually not life-threatening. In some cases, cancer cells are inherently resistant to certain drugs. This is known as intrinsic or primary resistance. The genetic makeup of these cells may make them less susceptible to the drug's mechanism of action.