Revista de SIDA e investigación clínica

HIV-Associated Malignancy Mechanisms and Oncogenic Proteomics Approaches for Translational Research

Abstract

Eduroe Derets

HIV infection is a global health concern that not only compromises the immune system but also increases the risk of developing malignancies. People Living With HIV (PLWH) are more susceptible to certain types of cancers, collectively referred to as HIV-associated malignancies. The mechanisms underlying the development of these malignancies in the context of HIV infection are complex and multifactorial. Understanding the oncogenic pathways involved and identifying potential biomarkers is crucial for translational research and the development of targeted therapies. This article provides a comprehensive overview of the mechanisms underlying HIV-associated malignancies and highlights the role of oncogenic proteomics in advancing translational research.