Revista de SIDA e investigación clínica

HIV-1 Drug Resistance Mutations Found in Patients with Treatment Failure in Russia\'s Northwestern Federal District

Abstract

Aoerse Yete

HIV/AIDS remains a global public health challenge, with millions of people worldwide living with the virus. Effective Antiretroviral Therapy (ART) has transformed HIV into a manageable chronic condition, enhancing the quality of life and extending the lifespan of those affected. However, the emergence of drug resistance mutations in the HIV-1 virus poses a significant threat to the success of ART. This article delves into a study conducted in Russia's Northwestern Federal District, focusing on the prevalence and implications of HIV-1 drug resistance mutations among patients experiencing treatment failure. Russia has been grappling with an expanding HIV epidemic for several years. The country has the highest number of new HIV infections in Eastern Europe and Central Asia, with the Northwestern Federal District being one of the regions most severely affected.