Revista de ciencias e ingeniería de materiales

Flexible screen-printed electrodes with stone paper as a substrate for electrochemical detection of cancer biomarker.

Abstract

Codruta Varodi

Flexible electrodes printed on stone paper (HP) and modified with gold nanoparticles (HP-AuNPs) and graphene (HP-Gr-AuNPs) were manufactured. Their electrochemical properties were studied by linear sweep voltammetry (LSV) and electrochemical impedance spectroscopy (EIS). The obtained results indicate the beneficial effect of AuNPs and graphene: a low charge transfer resistance and a high apparent heterogeneous electron transfer rate, compared to the unmodified electrode (HP). In addition, the modified electrodes showed increased sensitivity towards 8-OHdG, such as 5.90 mA/M (for HP-AuNPs) and 9.29 mA/M (for HP-Gr-AuNPs), in comparison with the unmodified HP electrode (2.52 mA/M).