José Antonio Roldán Nofuentes, Juan de Dios Luna Del Castillo and Miguel Angel Montero Alonso
Sensitivity and specificity are classic parameters to assess and to compare the precision of binary diagnostic tests in relation to a gold standard. Another parameter to assess and to compare the performance of binary diagnostic tests is the weighted kappa coefficient, which is a measure of the beyond-chance agreement between the binary diagnostic test and the gold standard, and it is a function of the sensitivity and the specificity of the diagnostic test, the disease prevalence and the relative loss between the false positives and the false negatives. In this study, we carry out a review of the weighted kappa coefficient, its estimation for a single diagnostic test and the hypothesis tests to compare the
weighted kappa coefficients of two or more diagnostic tests, both when the gold standard is applied to all of the subjects in a random sample and when the gold standard is only applied to a subset of subjects in a random sample. The results were applied to different examples.Comparte este artículo
English 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi 