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Cytotoxicity of Bismuth Compounds to Cultured Cancer Cells

Abstract

Jun Kobayashi, Keiichi Ikeda and Hideo Sugiyama

Bismuth (Bi) is a ubiquitous metal, but its effects on human health are unknown. We examined the cytotoxicity of Bi compounds to cultured 8505C human thyroid cancer cells. Treatments of 0.05–0.1 mM of Bi subgallate and free gallic acid resulted in cell death in approximately 100% of cells.

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