Revista de práctica general

Cutting-Edge Strategies in Massive Transfusion in Patients of Obstetric Hemorrhage

Abstract

Ritcha Saxena, Ananya Saxena, Ritwik Raj, Terrence Marcelle

Obstetric hemorrhage is a life-threatening complication which may occur without warning, predictive signs and symptoms, and even in absence of predisposing conditions. It is a major cause of maternal mortality and morbidity almost invariably among all human races. One of the most important strategies in the control of obstetric hemorrhage is hemostatic resuscitation. The speed with which obstetric hemorrhage occurs makes it lifethreatening, but thankfully, it can be successfully managed with blood transfusion protocol based management. Resuscitation of massive hemorrhage has shifted towards the earlier administration of higher doses of fresh frozen plasma (FFP) and reducing serious complications and mortality by limiting the conventional use of crystalloids and colloids. In this article, we explored the leading-edge strategy of use of fibrinogen concentrates, cryoprecipitates, Tranexamic acid and prothrombin complex concentrates, apart from fresh frozen plasma as a promising alternative for obstetric resuscitation and for minimizing the risks and complications of obstetric hemorrhage.