Revista de investigación del cerebro

Cerebral Venous Thrombosis and Sickle Cell (SC) Disease: Case Report and Literature Review

Abstract

Herve Guinhouya

The authors report a case of cerebral venous thrombosis in a thirty-seven-year-old sickle cell (SC) patient, who presented with a confusional state during hospitalization for a non-displaced fracture of the right leg. Exploration of the patient by cerebral CT and MRI brain angiography revealed superior sagittal sinus thrombosis. Biological examinations did not reveal any other hereditary or acquired hypercoagulable condition. The evolution was favorable under effective anticoagulation by low molecular weight heparin with per os relay by xarelto (rivaroxaban). The interest of this file resides in the scarcity of this observation in Black Africa, where, however, Sickle cell disease occurs.