Revista de enfermedades coronarias

Cardiovascular Complications of Diabetes Mellitus: Mechanisms and Novel Treatment Approaches

Abstract

Laura Vero*

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia and insulin resistance, affecting millions of people worldwide. One of the most significant and life-threatening complications of diabetes is cardiovascular disease (CVD). This research article aims to provide a comprehensive overview of the mechanisms underlying the development of cardiovascular complications in diabetes and explore novel treatment approaches that hold promise for mitigating these risks. We discuss the intricate interplay of various factors, including hyperglycemia, insulin resistance, inflammation, oxidative stress, and dyslipidemia, in the pathogenesis of diabetic cardiovascular complications. Additionally, we review recent advancements in therapeutic strategies, such as novel drugs, lifestyle modifications, and personalized medicine, that have the potential to improve cardiovascular outcomes in individuals with diabetes.