Investigaciones e Informes en Ciencias Médicas

An Innovative Treatment Strategy for Primary Cervical Diffuse Large B-Cell Lymphoma is Hysteroscopic Resection Followed by Adjuvant Radiotherapy

Abstract

Guglielmo Carlucci

Female genital tract involvement can occur as a subsequent symptom of disseminated lymphomas or leukaemia, although primary extranodal lymphoma sites are extremely rare. Primary lymphomas of the female genital tract can develop in the vulva, vagina, adnexa, uterine corpus, or uterine cervix. Primary malignant lymphomas make up only 0.008% of cervical tumours. The presenting symptoms are vague and can sometimes be associated with much more widespread conditions affecting the female genital tract. Typically, cervical cytology is negative. Deep cervical biopsy is necessary for preoperative diagnosis. Regarding the best course of action, there is no agreement to date. Surgery, chemotherapy, and radiotherapy are all utilised in various combinations. We present the first instance of a primary cervical diffuse large B-cell lymphoma treated by an immediate hysteroscopic excision that has been documented in the literature adjuvant radiotherapy is then given. The pertinent literature was examined. In the future, our cautious approach needs to be supported, especially for women who want children and for people with low performance status. Our patient is still free of disease 24 months after being diagnosed.